HPV DNA methylation at the early promoter and E1/E2 integrity: A comparison between HPV16, HPV18 and HPV45 in cervical cancer

Objectives: To compare and describe type-specific characteristics of HPV16, HPV18 and HPV45 in cervical cancer with respect to 3′LCR methylation and disruption of E1/E2. Methods: The methylation level of 137 cervical cancer samples (70 with HPV16, 37 with HPV18, and 30 with HPV45) of Brazilian patie...

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Bibliographic Details
Main Authors: Sérgio Menezes Amaro-Filho, Cláudia Bessa Pereira Chaves, Shayany Pinto Felix, Diogo Lisbôa Basto, Liz Maria de Almeida, Miguel Angelo Martins Moreira
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Papillomavirus Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2405852118300107