Ovarian Cancer-Cell Pericellular Hyaluronan Deposition Negatively Impacts Prognosis of Ovarian Cancer Patients

Ovarian Cancer-Cell Pericellular Hyaluronan Deposition Negatively Impacts Prognosis of Ovarian Cancer Patients

Background: Hyaluronan (HA), a component of the extracellular matrix, is frequently increased under pathological conditions including cancer. Not only stroma cells but also cancer cells themselves synthesize HA, and the interaction of HA with its cognate receptors promotes malignant progression and...

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Bibliographic Details
Main Authors: Leticia Oliveira-Ferrer, Barbara Schmalfeldt, Johannes Dietl, Catharina Bartmann, Udo Schumacher, Christine Stürken
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
ovarian cancer
stromal hyaluronan
tumor-associated hyaluronan staining pattern
hyaluronan-related enzymes
Online Access:https://www.mdpi.com/2227-9059/10/11/2944

Internet

https://www.mdpi.com/2227-9059/10/11/2944

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