Decreased Intrathecal Concentrations of Free Light Chains Kappa in Multiple Sclerosis Patients Taking Very High Effective Disease-Modifying Treatment

Decreased Intrathecal Concentrations of Free Light Chains Kappa in Multiple Sclerosis Patients Taking Very High Effective Disease-Modifying Treatment

Free light chains kappa (FLCκ) in cerebrospinal fluid (CSF) are a part of the intrathecal immune response. This observational study was conducted to investigate the effects of different disease-modifying therapies (DMT) on the humoral intrathecal immune response in the CSF of patients with multiple...

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Bibliographic Details
Main Authors: Marie Süße, Franz Felix Konen, Philipp Schwenkenbecher, Kathrin Budde, Matthias Nauck, Matthias Grothe, Malte Johannes Hannich, Thomas Skripuletz
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Diagnostics
Subjects:
cerebrospinal fluid
immunoglobulin synthesis
free light chain kappa
oligoclonal IgG
multiple sclerosis
disease-modifying therapy
Online Access:https://www.mdpi.com/2075-4418/12/3/720

Internet

https://www.mdpi.com/2075-4418/12/3/720

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