High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins

High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins

Abstract Staphylococcus aureus virulence has been associated with the production of phenol-soluble modulins (PSMs). These PSMs have distinct virulence functions and are known to activate, attract and lyse neutrophils. These PSM-associated biological functions are inhibited by lipoproteins in vitro....

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Main Authors: Josefien W. Hommes, Rachel M. Kratofil, Sigrid Wahlen, Carla J. C. de Haas, Reeni B. Hildebrand, G. Kees Hovingh, Micheal Otto, Miranda van Eck, Menno Hoekstra, Suzanne J. A. Korporaal, Bas G. J. Surewaard
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94651-1

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https://doi.org/10.1038/s41598-021-94651-1

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