Concurrent Blockade of Endothelial EGFR and VEGF Signaling on Malignant Associated Pleural Fluid Induced Angiogenesis: From Clinic to Bench

Concurrent Blockade of Endothelial EGFR and VEGF Signaling on Malignant Associated Pleural Fluid Induced Angiogenesis: From Clinic to Bench

Malignant-associated pleural fluid (MAPF) represented an unsolved problem in advanced lung cancer. Our previous work characterized increased pleural angiogenesis in lung adenocarcinoma and the propensity of MAPF on endothelial angiogenesis. This study investigated the combined efficacy of the tyrosi...

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Bibliographic Details
Main Authors: Wei-Teing Chen, Yu-Huei Lin, Chih-Ying Changchien, Ying Chen, Hsin-Han Chang, Wen-Chiuan Tsai, Hao-Chung Tsai, Chieh-Yung Wang, Ming-Sheng Shen, Li-Ting Cheng, Chen-Liang Tsai
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomedicines
Subjects:
lung cancer
malignant associated pleural effusion
vascular endothelium
EGFR
gefitinib
bevacizumab
Online Access:https://www.mdpi.com/2227-9059/9/10/1327

Internet

https://www.mdpi.com/2227-9059/9/10/1327

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