The asymmetry of female meiosis reduces the frequency of inheritance of unpaired chromosomes

Trisomy, the presence of a third copy of one chromosome, is deleterious and results in inviable or defective progeny if passed through the germ line. Random segregation of an extra chromosome is predicted to result in a high frequency of trisomic offspring from a trisomic parent. Caenorhabditis eleg...

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Bibliographic Details
Main Authors: Daniel B Cortes, Karen L McNally, Paul E Mains, Francis J McNally
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06056