Tuning the Biological Activity of Camphorimine Complexes through Metal Selection

Tuning the Biological Activity of Camphorimine Complexes through Metal Selection

The cytotoxic activity of four sets of camphorimine complexes based on the Cu(I), Cu(II), Ag(I), and Au(I) metal sites were assessed against the cisplatin-sensitive A2780 and OVCAR3 ovarian cancer cells. The results showed that the gold complexes were ca. one order of magnitude more active than the...

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Bibliographic Details
Main Authors: Joana P. Costa, Teresa Pinheiro, Maria S. Martins, M. Fernanda N. N. Carvalho, Joana R. Feliciano, Jorge H. Leitão, Rafaela A. L. Silva, Joana F. Guerreiro, Luís M. C. Alves, Inês Custódio, João Cruz, Fernanda Marques
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Antibiotics
Subjects:
camphorimine complexes
cytotoxic activity
toxicity
PIXE
ROS
Online Access:https://www.mdpi.com/2079-6382/11/8/1010

Internet

https://www.mdpi.com/2079-6382/11/8/1010

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