Bioluminescence Color-Tuning Firefly Luciferases: Engineering and Prospects for Real-Time Intracellular pH Imaging and Heavy Metal Biosensing

Firefly luciferases catalyze the efficient production of yellow-green light under normal physiological conditions, having been extensively used for bioanalytical purposes for over 5 decades. Under acidic conditions, high temperatures and the presence of heavy metals, they produce red light, a proper...

Full description

Bibliographic Details
Main Authors: Vadim R. Viviani, Gabriel F. Pelentir, Vanessa R. Bevilaqua
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/12/6/400