Study of Biological Activities and ADMET-Related Properties of Salicylanilide-Based Peptidomimetics

Study of Biological Activities and ADMET-Related Properties of Salicylanilide-Based Peptidomimetics

A series of eleven benzylated intermediates and eleven target compounds derived from salicylanilide were tested against <i>Staphylococcus aureus</i> ATCC 29213 and <i>Enterococcus faecalis</i> ATCC 29212 as reference strains and against three clinical isolates of methicillin-...

Full description

Bibliographic Details
Main Authors: Dominika Pindjakova, Eliska Pilarova, Karel Pauk, Hana Michnova, Jan Hosek, Pratibha Magar, Alois Cizek, Ales Imramovsky, Josef Jampilek
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
salicylamide
peptidomimetics
antimicrobial activity
cytotoxicity
lipophilicity
structure–activity relationships
Online Access:https://www.mdpi.com/1422-0067/23/19/11648

Internet

https://www.mdpi.com/1422-0067/23/19/11648

Similar Items