ATRA treatment slowed P-selectin-mediated rolling of flowing HL60 cells in a mechano-chemical-dependent manner

ATRA treatment slowed P-selectin-mediated rolling of flowing HL60 cells in a mechano-chemical-dependent manner

All-trans retinoic acid (ATRA)-induced differentiation of acute promyelocytic leukemia (APL) toward granulocytes may trigger APL differentiation syndrome (DS), but there is less knowledge about the mechano-chemical regulation mechanism of APL DS under the mechano-microenvironment. We found that ATRA...

Full description

Bibliographic Details
Main Authors: Xiaoting Dong, Shiping Peng, Yingchen Ling, Bing Huang, Wenjian Tu, Xiaoxi Sun, Quhuan Li, Ying Fang, Jianhua Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
HL60 cell
neutrophils
ATRA
differentiation
cell adhesion
fluid shear stress
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1148543/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1148543/full

Similar Items