Inhibition of Tryptophan Catabolism Is Associated With Neuroprotection During Zika Virus Infection

Inhibition of Tryptophan Catabolism Is Associated With Neuroprotection During Zika Virus Infection

Zika virus (ZIKV) is an arbovirus belonging to Flaviviridae family that emerged as a global health threat due to its association with microcephaly and other severe neurological complications, including Guillain-Barré Syndrome (GBS) and Congenital Zika Syndrome (CZS). ZIKV disease has been linked to...

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Bibliographic Details
Main Authors: Fernanda Martins Marim, Danielle Cunha Teixeira, Celso Martins Queiroz-Junior, Bruno Vinicius Santos Valiate, Jose Carlos Alves-Filho, Thiago Mattar Cunha, Robert Dantzer, Mauro Martins Teixeira, Antonio Lucio Teixeira, Vivian Vasconcelos Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Zika virus
IDO-1
neuroinflammation
neuronal death
microgliosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.702048/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.702048/full

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