Actin alpha 2, smooth muscle, a transforming growth factor-β1-induced factor, regulates collagen production in human periodontal ligament cells via Smad2/3 pathway

Actin alpha 2, smooth muscle, a transforming growth factor-β1-induced factor, regulates collagen production in human periodontal ligament cells via Smad2/3 pathway

Background/purpose: Actin alpha 2, smooth muscle (ACTA2) is an actin isoform that forms the cytoskeleton. Actin plays a crucial role in numerous cellular functions. ACTA2 is a marker of functional periodontal ligament (PDL) fibroblasts and is upregulated by transforming growth factor-β1 (TGF-β1); ho...

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Bibliographic Details
Main Authors: Naati Fakatava, Hiromi Mitarai, Asuka Yuda, Akira Haraguchi, Hiroko Wada, Daigaku Hasegawa, Hidefumi Maeda, Naohisa Wada
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Journal of Dental Sciences
Subjects:
ACTA2
Collagen production
Periodontal ligament
Smad2/3
TGF-β1
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790222002136

Internet

http://www.sciencedirect.com/science/article/pii/S1991790222002136

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