Genetic susceptibility to multiple sclerosis: interactions between conserved extended haplotypes of the MHC and other susceptibility regions

Genetic susceptibility to multiple sclerosis: interactions between conserved extended haplotypes of the MHC and other susceptibility regions

Abstract Background To study the accumulation of MS-risk resulting from different combinations of MS-associated conserved-extended-haplotypes (CEHs) of the MHC and three non-MHC “risk-haplotypes” nearby genes EOMES, ZFP36L1, and CLEC16A. Many haplotypes are MS-associated despite having population-fr...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: D. S. Goodin, P. Khankhanian, P. A. Gourraud, N. Vince
Format: Artykuł
Język:English
Wydane: BMC 2021-07-01
Seria:BMC Medical Genomics
Hasła przedmiotowe:
Genetic
Susceptibility
Multiple sclerosis
Risk
Additive
Multiplicative
Dostęp online:https://doi.org/10.1186/s12920-021-01018-6

Internet

https://doi.org/10.1186/s12920-021-01018-6

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