PSAT1 is upregulated by METTL3 to attenuate high glucose-induced retinal pigment epithelial cell apoptosis and oxidative stress

Abstract Background Diabetic retinopathy (DR) is a major ocular complication of diabetes mellitus, and a significant cause of visual impairment and blindness in adults. Phosphoserine aminotransferase 1 (PSAT1) is an enzyme participating in serine synthesis, which might improve insulin signaling and...

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Bibliographic Details
Main Authors: Xiaofeng Du, Yanting Wang, Fan Gao
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Diagnostic Pathology
Subjects:
Online Access:https://doi.org/10.1186/s13000-024-01556-4