The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer

The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer

Abstract Background The androgen receptor (AR) is a tumor suppressor in estrogen receptor (ER) positive breast cancer, a role sustained in some ER negative breast cancers. Key factors dictating AR genomic activity in a breast context are largely unknown. Herein, we employ an unbiased chromatin immun...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Leila Hosseinzadeh, Zoya Kikhtyak, Geraldine Laven-Law, Stephen M. Pederson, Caroline G. Puiu, Clive S. D’Santos, Elgene Lim, Jason S. Carroll, Wayne D. Tilley, Amy R. Dwyer, Theresa E. Hickey
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: BMC 2024-02-01
Sarja:Genome Biology
Aiheet:
Androgen receptor
GATA3
Breast
Luminal lineage
Linkit:https://doi.org/10.1186/s13059-023-03161-y

Internet

https://doi.org/10.1186/s13059-023-03161-y

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