The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis

The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis

Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by the absence of commonly targeted receptors. Unspecific chemotherapy is currently the main therapeutic option, with poor results. Another major challenge is the frequent appearance of brain metastasis (BM) associated with...

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Bibliographic Details
Main Authors: Marco Cavaco, Clara Pérez-Peinado, Javier Valle, Ruben D.M. Silva, Lurdes Gano, João D.G. Correia, David Andreu, Miguel A.R.B. Castanho, Vera Neves
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Anticancer peptides
BBB peptide shuttle
Blood-brain barrier
Brain metastasis
Cell-penetrating peptides
PepH3
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224004578

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http://www.sciencedirect.com/science/article/pii/S0753332224004578

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