Decoding Single Cell Morphology in Osteotropic Breast Cancer Cells for Dissecting Their Migratory, Molecular and Biophysical Heterogeneity

Decoding Single Cell Morphology in Osteotropic Breast Cancer Cells for Dissecting Their Migratory, Molecular and Biophysical Heterogeneity

Breast cancer is a heterogeneous disease and the mechanistic framework for differential osteotropism among intrinsic breast cancer subtypes is unknown. Hypothesizing that cell morphology could be an integrated readout for the functional state of a cancer cell, we established a catalogue of the migra...

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Bibliographic Details
Main Authors: Lila Bemmerlein, Ilker A. Deniz, Jana Karbanová, Angela Jacobi, Stephan Drukewitz, Theresa Link, Andy Göbel, Lisa Sevenich, Anna V. Taubenberger, Pauline Wimberger, Jan Dominik Kuhlmann, Denis Corbeil
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
bone metastasis
atomic force microscopy
breast cancer cell
cell morphology
lectin
migration
Online Access:https://www.mdpi.com/2072-6694/14/3/603

Internet

https://www.mdpi.com/2072-6694/14/3/603

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