Role of dopamine in the pathophysiology of Parkinson’s disease

Role of dopamine in the pathophysiology of Parkinson’s disease

Abstract A pathological feature of Parkinson’s disease (PD) is the progressive loss of dopaminergic neurons and decreased dopamine (DA) content in the substantia nigra pars compacta in PD brains. DA is the neurotransmitter of dopaminergic neurons. Accumulating evidence suggests that DA interacts wit...

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Bibliographic Details
Main Authors: Zhi Dong Zhou, Ling Xiao Yi, Dennis Qing Wang, Tit Meng Lim, Eng King Tan
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Translational Neurodegeneration
Subjects:
Dopamine
Dopamine quinones
3,4-Dihydroxyphenylacetaldehyde
Neurodegeneration
Pathogenesis
Parkinson's disease
Online Access:https://doi.org/10.1186/s40035-023-00378-6

Internet

https://doi.org/10.1186/s40035-023-00378-6

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