Transdermal Delivery of Lidocaine-Loaded Elastic Nano-Liposomes with Microneedle Array Pretreatment

Transdermal Delivery of Lidocaine-Loaded Elastic Nano-Liposomes with Microneedle Array Pretreatment

This study aimed to improve the transdermal delivery of lidocaine hydrochloride (LidH) using elastic nano-liposomes (ENLs) and microneedle (MN) array pretreatment. LidH-containing ENLs were prepared using soybean phosphatidylcholine and cholesterol, with Span 80 or Tween 80, using a reverse-phase ev...

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Bibliographic Details
Main Authors: Yang Liu, Maosen Cheng, Junqi Zhao, Xiaoying Zhang, Zhen Huang, Yuhui Zang, Ying Ding, Junfeng Zhang, Zhi Ding
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
lidocaine
solid microneedles
elastic vesicles
topical drug administration
anesthesia
Online Access:https://www.mdpi.com/2227-9059/9/6/592

Internet

https://www.mdpi.com/2227-9059/9/6/592

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