The Potential Role of Protein Kinase R as a Regulator of Age-Related Neurodegeneration

There is a growing evidence describing a decline in adaptive homeostasis in aging-related diseases affecting the central nervous system (CNS), many of which are characterized by the appearance of non-native protein aggregates. One signaling pathway that allows cell adaptation is the integrated stres...

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Bibliographic Details
Main Authors: Nicolás W. Martinez, Felipe E. Gómez, Soledad Matus
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.638208/full