The Val66 and Met66 Alleles-Specific Expression of BDNF in Human Muscle and Their Metabolic Responsivity

The Val66 and Met66 Alleles-Specific Expression of BDNF in Human Muscle and Their Metabolic Responsivity

Brain-derived neurotrophic factor (BDNF) plays an essential role in nervous system formation and functioning, including metabolism. Present only in humans, the “Val66Met” polymorphism of the BDNF gene (BDNF) is suggested to have a negative influence on the etiology of neurological diseases. However,...

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Bibliografische gegevens
Hoofdauteurs: Gilmara Gomes de Assis, Jay R. Hoffman, Jacek Bojakowski, Eugenia Murawska-Ciałowicz, Paweł Cięszczyk, Eugene V. Gasanov
Formaat: Artikel
Taal:English
Gepubliceerd in: Frontiers Media S.A. 2021-05-01
Reeks:Frontiers in Molecular Neuroscience
Onderwerpen:
Val66Met polymorphism
BDNF
allele-specific gene expression
mRNA level
metabolism
VO2max test
Online toegang:https://www.frontiersin.org/articles/10.3389/fnmol.2021.638176/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2021.638176/full

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