The Long Pentraxin PTX3 as a New Biomarker and Pharmacological Target in Age-Related Macular Degeneration and Diabetic Retinopathy

The Long Pentraxin PTX3 as a New Biomarker and Pharmacological Target in Age-Related Macular Degeneration and Diabetic Retinopathy

Age related macular degeneration (AMD) and diabetic retinopathy (DR) are multifactorial, neurodegenerative and inflammatory diseases of the eye primarily involving cellular and molecular components of the outer and inner blood-retina barriers (BRB), respectively. Largely contributed by genetic facto...

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Bibliographic Details
Main Authors: Matteo Stravalaci, Mariantonia Ferrara, Varun Pathak, Francesca Davi, Barbara Bottazzi, Alberto Mantovani, Reinhold J. Medina, Mario R. Romano, Antonio Inforzato
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
age-related macular degeneration
diabetic retinopathy
complement
inflammation
PTX3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.811344/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.811344/full

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