Safety and biodegradability of a synthetic dural sealant patch (Liqoseal) in a porcine cranial model

Abstract Background Liqoseal consists of a watertight layer of poly(ester)ether urethane and an adhesive layer containing polyethylene glycol‐N‐hydroxysuccinimide (PEG‐NHS). It is designed to prevent cerebrospinal fluid (CSF) leakage after intradural surgery. This study assessed the safety and biode...

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Bibliographic Details
Main Authors: Ahmet Kinaci, Wilhelmina Bergmann, Sander vanThoor, Saskia Redegeld, Albert van derZwan, Tristan P. C. vanDoormaal
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Animal Models and Experimental Medicine
Subjects:
Online Access:https://doi.org/10.1002/ame2.12184