Tracking W-Formate Dehydrogenase Structural Changes During Catalysis and Enzyme Reoxidation

Tracking W-Formate Dehydrogenase Structural Changes During Catalysis and Enzyme Reoxidation

Metal-dependent formate dehydrogenases (Fdh) catalyze the reversible conversion of CO<sub>2</sub> to formate, with unrivalled efficiency and selectivity. However, the key catalytic aspects of these enzymes remain unknown, preventing us from fully benefiting from their capabilities in ter...

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Bibliographic Details
Main Authors: Guilherme Vilela-Alves, Rita Rebelo Manuel, Ana Rita Oliveira, Inês Cardoso Pereira, Maria João Romão, Cristiano Mota
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
formate dehydrogenase
CO<sub>2</sub> reduction
X-ray crystallography
molybdopterin
tungsten cofactor
redox enzymes
Online Access:https://www.mdpi.com/1422-0067/24/1/476

Internet

https://www.mdpi.com/1422-0067/24/1/476

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