Pneumolysin as a target for new therapies against pneumococcal infections: A systematic review.

<h4>Background</h4>This systematic review evaluates pneumolysin (PLY) as a target for new treatments against pneumococcal infections. Pneumolysin is one of the main virulence factors produced by all types of pneumococci. This toxin (53 kDa) is a highly conserved protein that binds to cho...

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Bibliographic Details
Main Authors: María Dolores Cima Cabal, Felipe Molina, José Ignacio López-Sánchez, Efrén Pérez-Santín, María Del Mar García-Suárez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0282970