Monoubiquitination and activity of the paracaspase MALT1 requires glutamate 549 in the dimerization interface.

Monoubiquitination and activity of the paracaspase MALT1 requires glutamate 549 in the dimerization interface.

The mucosa-associated lymphoid tissue protein-1 (MALT1, also known as paracaspase) is a protease whose activity is essential for the activation of lymphocytes and the growth of cells derived from human diffuse large B-cell lymphomas of the activated B-cell subtype (ABC DLBCL). Crystallographic appro...

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Bibliographic Details
Main Authors: Katrin Cabalzar, Christiane Pelzer, Annette Wolf, Georg Lenz, Justyna Iwaszkiewicz, Vincent Zoete, Stephan Hailfinger, Margot Thome
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3747146?pdf=render

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http://europepmc.org/articles/PMC3747146?pdf=render

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