Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways
Abstract Cystic fibrosis is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) that can lead to terminal respiratory failure. Ultrafine carbonaceous particles, which are ubiquitous in ambient urban and indoor air, are increasingly co...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-08-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-18098-8 |