Increased concentrations of conjugated bile acids are associated with osteoporosis in PSC patients

Abstract Primary sclerosing cholangitis (PSC) is an idiopathic cholestatic liver disease characterized by chronic inflammation and progressive fibrosis of intra- and extrahepatic bile ducts. Osteoporosis is a frequent comorbidity in PSC, and we could previously demonstrate that IL17-dependent activa...

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Bibliographic Details
Main Authors: Julian Stürznickel, Friederike Behler-Janbeck, Anke Baranowsky, Tobias Schmidt, Dorothee Schwinge, Clara John, Ansgar W. Lohse, Christoph Schramm, Joerg Heeren, Thorsten Schinke, Michael Amling
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20351-z