Network pharmacology- and molecular docking-based approach for predicting key targets and the potential mechanism of Tripterygium wilfordii Hook F for the treatment of acute lymphoblastic leukaemia

This study explored the main active ingredients and the underlying mechanism of TwHF in the treatment of ALL by network pharmacology and molecular docking. TCMSP, OMIM and GeneCards databases were used to obtain active ingredients of TwHF to predict related targets of TwHF and ALL. Cytoscape and STR...

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Bibliographic Details
Main Authors: Xi Li, Xiang Qin, Tingting Fang, Wenjun Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:All Life
Subjects:
Online Access:http://dx.doi.org/10.1080/26895293.2022.2147220