Biallelic non-productive enhancer-promoter interactions precede imprinted expression of Kcnk9 during mouse neural commitment

Biallelic non-productive enhancer-promoter interactions precede imprinted expression of Kcnk9 during mouse neural commitment

Summary: It is only partially understood how constitutive allelic methylation at imprinting control regions (ICRs) interacts with other regulation levels to drive timely parental allele-specific expression along large imprinted domains. The Peg13-Kcnk9 domain is an imprinted domain with important br...

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Bibliographic Details
Main Authors: Cecilia Rengifo Rojas, Jil Cercy, Sophie Perillous, Céline Gonthier-Guéret, Bertille Montibus, Stéphanie Maupetit-Méhouas, Astrid Espinadel, Marylou Dupré, Charles C. Hong, Kenichiro Hata, Kazuhiko Nakabayashi, Antonius Plagge, Tristan Bouschet, Philippe Arnaud, Isabelle Vaillant, Franck Court
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:HGG Advances
Subjects:
genomic imprinting
chromatin looping
brain-specific expression
remote transcriptional control
Birk-Barel
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247724000101

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http://www.sciencedirect.com/science/article/pii/S2666247724000101

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