A scalable system for generation of mesenchymal stem cells derived from induced pluripotent cells employing bioreactors and degradable microcarriers

A scalable system for generation of mesenchymal stem cells derived from induced pluripotent cells employing bioreactors and degradable microcarriers

Abstract Human mesenchymal stem cells (hMSCs) are effective in treating disorders resulting from an inflammatory or heightened immune response. The hMSCs derived from induced pluripotent stem cells (ihMSCs) share the characteristics of tissue derived hMSCs but lack challenges associated with limited...

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Bibliographic Details
Main Authors: Robert E. Rogers, Andrew Haskell, Berkley P. White, Sujata Dalal, Megan Lopez, Daniel Tahan, Simin Pan, Gagandeep Kaur, Hyemee Kim, Heather Barreda, Susan L. Woodard, Oscar R. Benavides, Jing Dai, Qingguo Zhao, Kristen C. Maitland, Arum Han, Zivko L. Nikolov, Fei Liu, Ryang Hwa Lee, Carl A. Gregory, Roland Kaunas
Format: Article
Language:English
Published: Oxford University Press 2021-12-01
Series:Stem Cells Translational Medicine
Subjects:
bioreactor
immunomodulatory
induced pluripotent stem cells
mesenchymal stem cells
Online Access:https://doi.org/10.1002/sctm.21-0151

Internet

https://doi.org/10.1002/sctm.21-0151

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