Influence of oxygen concentration on the metabolism of Penicillium chrysogenum

Abstract In large‐scale bioreactors, there is often insufficient mixing and as a consequence, cells experience uneven substrate and oxygen levels that influence product formation. In this study, the influence of dissolved oxygen (DO) gradients on the primary and secondary metabolism of a high produc...

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Bibliographic Details
Main Authors: Agnes Janoska, Jelle J. Verheijen, Wenjung Tang, Queenie Lee, Baukje Sikkema, Walter M. van Gulik
Format: Article
Language:English
Published: Wiley-VCH 2023-01-01
Series:Engineering in Life Sciences
Subjects:
Online Access:https://doi.org/10.1002/elsc.202100139