1-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-pyrroles, Part II)

A bis(chloroethyl)amine-containing side chain is attached to an oxonaphthalene-annelated pyrrole in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.

Bibliographic Details
Main Authors: Christiane Puschmann, Helmut Spreitzer
Format: Article
Language:English
Published: MDPI AG 2010-01-01
Series:Molbank
Subjects:
n/a
Online Access:http://www.mdpi.com/1422-8599/2010/1/M654/