Short incubation periods of atypical H-type BSE in cattle with EK211 and KK211 prion protein genotypes after intracranial inoculation

In 2006, a case of atypical H-type BSE (H-BSE) was found to be associated with a germline mutation in the PRNP gene that resulted in a lysine substitution for glutamic acid at codon 211 (E211K). The E211K amino acid substitution in cattle is analogous to E200K in humans, which is associated with the...

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Bibliographic Details
Main Authors: Eric D. Cassmann, Alexis J. Frese, Kelsey A. Becker, Justin J. Greenlee
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1301998/full