siRNA Targeting the 2Apro Genomic Region Prevents Enterovirus 71 Replication In Vitro.

Enterovirus 71 (EV71) is the most important etiological agent of hand, foot, and mouth disease (HFMD) in young children, which is associated with severe neurological complications and has caused significant mortalities in recent HFMD outbreaks in Asia. However, there is no effective antiviral therap...

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Bibliographic Details
Main Authors: Haibing Liu, Yanyan Qin, Zhenzhen Kong, Qixiang Shao, Zhaoliang Su, Shengjun Wang, Jianguo Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4757562?pdf=render