Alzheimer's disease is associated with disruption in thiamin transport physiology: A potential role for neuroinflammation

Alzheimer's disease is associated with disruption in thiamin transport physiology: A potential role for neuroinflammation

Alzheimer's disease (AD) is a neurodegenerative disease characterized by Amyloid-β peptide (Aβ) containing plaques and cognitive deficits. The pathophysiology of AD also involves neuroinflammation. Vitamin B1 (thiamin) is indispensable for normal cellular energy metabolism. Thiamin homeostasis...

Full description

Bibliographic Details
Main Authors: Kalidas Ramamoorthy, Ryan Yoshimura, Saleh Al-Juburi, Kasin Y. Anandam, Rubina Kapadia, Amal Alachkar, Geoffrey W. Abbott, Hamid M. Said
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Thiamin transporters −1 and −2
Pro-inflammatory cytokines
Thiamin uptake
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122001917

Internet

http://www.sciencedirect.com/science/article/pii/S0969996122001917

Similar Items