Glucocorticoid Receptor Signaling in Diabetes

Glucocorticoid Receptor Signaling in Diabetes

Stress and depression increase the risk of Type 2 Diabetes (T2D) development. Evidence demonstrates that the Glucocorticoid (GC) negative feedback is impaired (GC resistance) in T2D patients resulting in Hypothalamic-Pituitary-Adrenal (HPA) axis hyperactivity and hypercortisolism. High GCs, in turn,...

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Bibliographic Details
Main Authors: Ioanna Kokkinopoulou, Andriana Diakoumi, Paraskevi Moutsatsou
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
glucocorticoids
glucocorticoid receptor
GR
diabetes mellitus
stress
Online Access:https://www.mdpi.com/1422-0067/22/20/11173

Internet

https://www.mdpi.com/1422-0067/22/20/11173

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