Enhanced Downstream Processing for a Cell-Based Avian Influenza (H5N1) Vaccine

Enhanced Downstream Processing for a Cell-Based Avian Influenza (H5N1) Vaccine

H5N1 highly pathogenic avian influenza virus (HPAIV) infections pose a significant threat to human health, with a mortality rate of around 50%. Limited global approval of H5N1 HPAIV vaccines, excluding China, prompted the need to address safety concerns related to MDCK cell tumorigenicity. Our objec...

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Bibliographic Details
Main Authors: Fang Li, Bo Liu, Yu Xiong, Zhegang Zhang, Qingmei Zhang, Ran Qiu, Feixia Peng, Xuanxuan Nian, Dongping Wu, Xuedan Li, Jing Liu, Ze Li, Hao Tu, Wenyi Wu, Yu Wang, Jiayou Zhang, Xiaoming Yang
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Vaccines
Subjects:
downstream purification process
H5N1
HPAIV
MDCK cells
Capto<sup>TM</sup> Core 700
hydrophobic chromatography
Online Access:https://www.mdpi.com/2076-393X/12/2/138

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https://www.mdpi.com/2076-393X/12/2/138

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