Analysis of differentially expressed genes discovers Latroeggtoxin VI-induced changes and SYNJ1 as a main target in PC12 cells

Analysis of differentially expressed genes discovers Latroeggtoxin VI-induced changes and SYNJ1 as a main target in PC12 cells

Abstract Background Previous preliminary work found that Latroeggtoxin-VI (LETX-VI), a proteinaceous neurotoxin from the eggs of spider Latrodectus tredecimguttatus, could promote the synthesis and release of dopamine in PC12 cells. However, the underlying mechanisms have not been fully clear. Here,...

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Bibliographic Details
Main Authors: Dianmei Yu, Haiyan Wang, Zhixiang Lei, Yiwen Zhai, Si Chen, Minglu Sun, Panfeng Yin, Xianchun Wang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Genomics
Subjects:
Latroeggtoxin-VI
Differential transcriptome
PC12 cell
Transcript-encoded protein
Dopamine
Synaptojanin 1
Online Access:https://doi.org/10.1186/s12864-023-09634-5

Internet

https://doi.org/10.1186/s12864-023-09634-5

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