Impairments of Long-Term Synaptic Plasticity in the Hippocampus of Young Rats during the Latent Phase of the Lithium-Pilocarpine Model of Temporal Lobe Epilepsy

Impairments of Long-Term Synaptic Plasticity in the Hippocampus of Young Rats during the Latent Phase of the Lithium-Pilocarpine Model of Temporal Lobe Epilepsy

Status epilepticus (SE) causes persistent abnormalities in the functioning of neuronal networks, often resulting in worsening epileptic seizures. Many details of cellular and molecular mechanisms of seizure-induced changes are still unknown. The lithium–pilocarpine model of epilepsy in rats reproduc...

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Bibliographic Details
Main Authors: Tatyana Y. Postnikova, Georgy P. Diespirov, Dmitry V. Amakhin, Elizaveta N. Vylekzhanina, Elena B. Soboleva, Aleksey V. Zaitsev
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
astrocyte
D-serine
temporal lobe epilepsy
NMDA
field potential
long-term potentiation
Online Access:https://www.mdpi.com/1422-0067/22/24/13355

Internet

https://www.mdpi.com/1422-0067/22/24/13355

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