Vanadium pentoxide induced oxidative stress and cellular senescence in human lung fibroblasts

Vanadium pentoxide induced oxidative stress and cellular senescence in human lung fibroblasts

Both environmental exposure to vanadium pentoxide (V2O5, V+5 for its ionic counterparts) and fibroblast senescence are associated with pulmonary fibrosis, but whether V+5 causes fibroblast senescence remains unknown. We found in a dose-response study that 2–40 μM V+5 caused human lung fibroblasts (H...

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Bibliographic Details
Main Authors: Xiaojia He, Zachery R. Jarrell, Yongliang Liang, Matthew Ryan Smith, Michael L. Orr, Lucian Marts, Young-Mi Go, Dean P. Jones
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Redox Biology
Subjects:
Environmental health
Lung fibrosis
Redox cycling
Thiol/disulfide redox
Vanadate
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001811

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http://www.sciencedirect.com/science/article/pii/S2213231722001811

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