Novel β-lactamase inhibitors: a therapeutic hope against the scourge of multidrug resistance

The increasing incidence and prevalence of multidrug resistance (MDR) among contemporary Gram-negative bacteria represents a significant threat to human health. Since their discovery, β-lactam antibiotics are a major component of the armamentarium against these serious pathogens. Unfortunately, a wi...

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Bibliographic Details
Main Authors: Richard eWatkins, Krisztina M. Papp-Wallace, Sarah M. Drawz, Robert Anthony Bonomo
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00392/full