Structural insights into molecular mechanism for N 6-adenosine methylation by MT-A70 family methyltransferase METTL4

Structural insights into molecular mechanism for N 6-adenosine methylation by MT-A70 family methyltransferase METTL4

Here the authors combine functional and structural work to show that METTL4 functions as U2 snRNA m6Am RNA methyltransferase supporting N6-methylation of 2’-O-methyladenosine in Arabidopsis.

Bibliographic Details
Main Authors: Qiang Luo, Jiezhen Mo, Hao Chen, Zetao Hu, Baihui Wang, Jiabing Wu, Ziyu Liang, Wenhao Xie, Kangxi Du, Maolin Peng, Yingping Li, Tianyang Li, Yangyi Zhang, Xiaoyan Shi, Wen-Hui Shen, Yang Shi, Aiwu Dong, Hailin Wang, Jinbiao Ma
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33277-x

Internet

https://doi.org/10.1038/s41467-022-33277-x

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