Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos.

The FLRT family of transmembrane proteins has been implicated in the regulation of FGF signalling, neurite outgrowth, homotypic cell sorting and cadherin-mediated adhesion. In an expression screen we identified the Netrin receptors Unc5B and Unc5D as high-affinity FLRT3 interactors. Upon overexpress...

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Bibliographic Details
Main Authors: Emil Karaulanov, Ralph T Böttcher, Peter Stannek, Wei Wu, Marlene Rau, Souichi Ogata, Ken W Y Cho, Christof Niehrs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2683942?pdf=render