Bispecific Antibodies for IFN-β Delivery to ErbB2<sup>+</sup> Tumors

The main aim of our work was to create a full-length bispecific antibody (BsAb) as a vehicle for the targeted delivery of interferon-beta (IFN-β) to ErbB2<sup>+</sup> tumor cells in the form of non-covalent complex of BsAb and IFN-β. Such a construct is a CrossMab-type BsAb, consisting o...

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Бібліографічні деталі
Автори: Vladislav S. Rybchenko, Anna A. Panina, Teimur K. Aliev, Olga N. Solopova, Dmitry S. Balabashin, Valery N. Novoseletsky, Dmitry A. Dolgikh, Petr G. Sveshnikov, Mikhail P. Kirpichnikov
Формат: Стаття
Мова:English
Опубліковано: MDPI AG 2021-12-01
Серія:Biomolecules
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Онлайн доступ:https://www.mdpi.com/2218-273X/11/12/1915