Brain Region Differences in α1- and α5-Subunit-Containing GABA<sub>A</sub> Receptor Proteomes Revealed with Affinity Purification and Blue Native PAGE Proteomics
GABA<sub>A</sub> receptors are the major inhibitory receptors in the brain. They are hetero-pentamers with a composition of predominantly two α, two β, and one γ or δ subunit. Of the six α subunit genes, the α5 subunit displays a limited spatial expression pattern and is known to mediate...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-12-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/13/1/14 |