Functional analysis of a putative HER2-associated expressed enhancer, Her2-Enhancer1, in breast cancer cells

Abstract HER-2/neu (HER2) is a member of the epidermal growth factor receptors family, encoding a protein with tyrosine kinase activity. Following the gene amplification or increased HER2 transcription, carcinogenesis has been observed in some cancers. Genetic and epigenetic changes occurring in enh...

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Bibliographic Details
Main Authors: Mahdieh Rojhannezhad, Bahram M. Soltani, Mohammad Vasei, Nassim Ghorbanmehr, Seyed Javad Mowla
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46460-x