Sufentanil attenuates inflammation and oxidative stress in myocardial ischemia reperfusion injury via upregulating Sestrin 2 expression and activating AMPK signalling pathway

Sufentanil attenuates inflammation and oxidative stress in myocardial ischemia reperfusion injury via upregulating Sestrin 2 expression and activating AMPK signalling pathway

This study explored whether sufentanil, a lipophilic opioid, can protect against myocardial ischemia-reperfusion (I/R) injury via regulating Sestrin 2 (Sesn2) expression. The expression of Sesn2 was measured in the blood of patients with myocardial I/R after sufentanil administration. H9c2 cells wer...

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Bibliographic Details
Main Authors: Ping Jiang, Zhiwei Zou, Renshu Tu, Shuo Wang, Huifang Yun
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
ischemia reperfusion
sufentanil
inflammation
oxidative stress
sestrin 2
Online Access:http://dx.doi.org/10.1080/13102818.2020.1728197

Internet

http://dx.doi.org/10.1080/13102818.2020.1728197

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