Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease.

Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease.

BACKGROUND:Recent studies showed that polymorphisms in the Fat and Obesity-Associated (FTO) gene have robust effects on obesity, obesity-related traits and endophenotypes associated with Alzheimer's disease (AD). METHODS:We used 1,877 Caucasian cases and controls from the NIA-LOAD study and 1,0...

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Bibliographic Details
Main Authors: Christiane Reitz, Giuseppe Tosto, Richard Mayeux, Jose A Luchsinger, NIA-LOAD/NCRAD Family Study Group, Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3520931?pdf=render

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http://europepmc.org/articles/PMC3520931?pdf=render

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