BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded in vitro

BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded in vitro

ABSTRACTBacillus Calmette-Guérin (BCG), the nonpathogenic Mycobacterium bovis strain used as tuberculosis vaccine, has been successfully used as treatment for non-muscle invasive bladder cancer for decades, and suggested to potentiate cellular and humoral immune responses. However, the exact mechani...

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Bibliographic Details
Main Authors: Gloria Esteso, María José Felgueres, Álvaro F. García-Jiménez, Christina Reyburn-Valés, Alberto Benguría, Enrique Vázquez, Hugh T. Reyburn, Nacho Aguiló, Carlos Martín, Eugenia Puentes, Ingrid Murillo, Esteban Rodríguez, Mar Valés-Gómez
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
Cancer immunology
BCG
NK activation
gamma delta T lymphocytes
bladder cancer
immunotherapy
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2160094

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2022.2160094

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